Kämpfender Krebs

Während seiner Eröffnungsadresse 1970 erklärte amerikanischer Präsident Richard Nixon a Krieg auf Krebs. Versprechen, mindestens $100 Million bei der Finanzierung zuzuteilen, zum nachzuforschen der Ursachen für, was dann die zweit-führende Ursache des Todes in den Vereinigten Staaten war, Nixon durch gefolgt 1971 vom Unterzeichnen Nationale Krebs-Tat. Schlüsselzielsetzungen von diesem Tat eingeschlossenes Hineingießen grundlegende Wissenschaften Forschung Finanzierung, Ramping herauf klinische Versuche und Lassen des nationalen Krebses einen freistehenden Körper unter den nationalen Instituten der Gesundheit einleiten.

Fast vierzig bilden Jahre später, ärzte und Wissenschaftler große Fortschritte, wenn es besser versteht ätiologie, Management und Behandlung in allen Formen des Krebses. Vor kurzem die amerikanische Gesellschaft für klinische Onkologie gab einen Report frei erlaubt, Klinischer Krebs rückt 2007 vor: Hauptforschung Fortschritte in der Krebs-Behandlung, der Verhinderung und der Siebung. Diese Jahresübersicht, die als .pdf, podcast und Slideshow an vorhanden ist Leute, die mit Krebsweb site leben, schließt die folgenden Höhepunkte ein: 

Primärleber-Krebs-Patienten erhalten die Wahl für Körperbehandlung: Bis vor kurzem waren chirurgische Techniken die erste Linie der Behandlung bei Leberkrebspatienten weil Antwort zur Chemotherapie war so schlecht. 2007 zeigten Resultate einer großen Studie diesen vorgerückten Leberkrebs mit sorafenib (Nevaxar), ein gerichtetes chemotherapeutisches, gelebt 44 Prozent länger als Patienten, die nicht. Mehr →

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Seiend die schwärmerisch verehrende (IE, Gezeter) ältere Schwester zu zwei Geschwister, die an Wissenschaft interessiert werden, kann ich Ihnen von der Erfahrung den erklären ist jetzt die Zeit für High School und die Studenten, zum Sommer Internships in der Krebsforschung zu beantragen!

Here’s a round-up of paid summer research internships at some of the biggest cancer centers in the US. Don’t forget to look at your local comprehensive cancer center to see if they sponsor research fellowships — both my brother and sister snagged one at our state’s university. They both found their time in the laboratory invaluable, and my brother has since then been inspired to pursue a career as a medical scientist.

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Chronic Illness is a journal that focuses on multi-disciplinary approaches to disease treatment and management.  This month, the journal focuses on childhood cancer.

Articles are available to the public for free viewing until May. I’ve listed links to them below, and I’ve found them to be a good mix of original scientific research, clinical observation, and the often forgotten patient / caregiver perspective. Definitely the best multi-disciplinary “round up” of current articles that I’ve seen on childhood cancer recently — check them out if you get a chance!

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I missed this the first time around, but Dr. Jose DeJesus over at Physician Entrepreneur recently covered an interesting new development in breast cancer reconstructive surgery using stem cells.

From “Stem Cell Breakthrough - New Possibilities in Breast Reconstruction and Augmentation:” More →

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Yesterday, my friend Carey wrote a little bit about her family’s experience with BRCA genetic testing. Recently, I read a related article over at Ramunus’ excellent Cancer Genetics blog entitled, “When Having BRCA Mutation is Not So Bad or Even Better.”

It’s a pretty good brief explanation of two new studies that challenge the conventional thinking of BCRA mutation = bad. Check it out!

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Hi everyone — pull up a comfy seat and get ready for some weekend reading. Here’s my favorite posts from the last few weeks from around the blogosphere!

When Your Stool Smells Bad and it Floats in the Toilet Bowl
A very, um, descriptive post about some post-treatment hazards for pancreatic cancer patients.

Cancer Doesn’t Wait ‘Till After the Holidays, Parts II and III
Karen Lynch of Discussing Breast Cancer finishes out a brilliant series on practical advice for

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It may not be as scandalous as getting naked for charity, but this is definitely a cause that I can get behind.

Mustaches for Kids is a volunteer organization of over a dozen chapters throughout North America that raises money for various children’s charities. Since its inception in 1999, its members have garnered sponsorships to support their facial hair efforts.

From the organization’s website:

Here’s how it works: Each year, during the four-week Growing Season between Thanksgiving and Christmas, Growers sprout sweet, sweet Mustaches. Per Mustaches for Kids bylaws, they shave their faces, except for the Mustache, a minimum of one time per week and solicit donations from friends, family, co-workers, and people in the community. Kind of like getting pledges to run a marathon. Without the exertion, cramping, or dehydration. Call it a facial hair marathon. More →

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A new study out this week aims to put a more individual spin on the mathematics behind tumor progression.

Niko Beerenwinkel and colleagues used a colon cancer case study to analyze how much particular gene mutations affect an individual’s tumor development. They found that current tumor progression models, which only looked at a few genes of interest, lacked the accuracy that a model based on a larger selection of gene mutations could provide.

Previously, doctors have relied heavily on standard mathematical formulas to derive predictions on how large individual tumors will grow in a particular amount of time. The article, which was published on November 9 in the Public Library of Science journal Computational Biology, may help explain the huge variation between individual tumors.

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Here’s a quick glance at a few interesting cancer research studies that have come out recently, edited here for your weekend reading pleasure — enjoy!

Transplanting killer cells into cancer patients: Apparently, there are some people just aren’t prone to getting cancer due to a higher than normal healthy stock of immune system soldiers called granulocytes. Wake Forest University-based Dr. Zheng Cuit and his colleagues are looking to see if they can transplant some of those natural born killer cells into cancer patients — um, as long as it’s not flu season.

Average cancer-killing ability appeared to be lower in adults over the age of 50 and even lower in people with cancer. It also fell when people were stressed, and at certain times of the year.

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When looking for quality information about medical or scientific breakthroughs, like most everything else in life, you have to sift through a lot of crap in order to find the good stuff. Unfortunately, for every good source on the internet about cancer like the American Cancer Society or WebMD, you have tons of sites and blogs with weak content or even misinformation.

Because physicians and scientists don’t often spend the time marketing their big ideas a la Benjamin Franklin or Thomas Edison, it’s often up to science writers, journalists, and bloggers to interpret their work and broadcast it for them. It is here where many roadblocks to good science communication can come up, including a lack of familiarity with a hyper-specialized vocabulary (be honest: do you recognize this?) or even a misintepretation of a data set’s significance (helpful hint for everyone who reports on medical breakthroughs in cancer research: correlation does not imply causation!)

Martin Fenner points out the difficulty of writing about cancer research science to a general audience in an interesting article entitled “Poor Media Coverage of Cancer Research: Are Blogs one Answer?” An excerpt:

For those of us working in cancer research, it is important to remember to communicate our research findings not only in journal articles and scientific meetings. We probably have to do a much better job in talking to the media and the public. One example would be to start a blog about a particular area of cancer research or cancer patient care. The number of quality blogs in this area could be much higher, and some blogs even had to close down.

I agree with Martin that there aren’t nearly enough high-quality news outlets for cancer research, and we’re not alone. This past year, one of the biggest powerhouses in scientific publications, the Nature Publishing Group, has made some pretty bold steps in making strong, evidence-based information about science easily accessible through their development of the Nature Network, an open-access social network and blogging platform geared directly to scientists and other professionals (including Martin).

In the spirit of promoting strong content in the world of cancer research, I’d like to point you to a few recent posts on some of my favorite blogs: More →

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